Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy

Maciej Gawęcki; Krzysztof Kiciński; Andrzej Grzybowski

doi:10.1016/j.aopr.2024.01.004

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Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy

Full Length Article | 更新时间：2024-05-29

- Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy
- AOPR Vol. 4, Issue 1, Pages: 32-38(2024)
- 作者机构：
  
  1. Dobry Wzrok Ophthalmological Clinic,Gdansk,Poland,80-822
  2. Department of Ophthalmology, Pomeranian Hospitals in Wejherowo, 84-200, Wejherowo,Poland
  3. ,Poznan,Poland
- 作者简介：
- 基金信息：
- DOI：10.1016/j.aopr.2024.01.004
  CLC：
- Published：2024，
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Maciej Gawęcki, Krzysztof Kiciński, Andrzej Grzybowski. Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy. [J]. AOPR 4(1):32-38(2024)
DOI：

Maciej Gawęcki, Krzysztof Kiciński, Andrzej Grzybowski. Crossover to PDT after the unsuccessful micropulse laser treatment of central serous chorioretinopathy. [J]. AOPR 4(1):32-38(2024) DOI： 10.1016/j.aopr.2024.01.004.

摘要

Abstract

PurposeSubthreshold micropulse laser (SML) and photodynamic therapy (PDT) are among the most effective therapeutic modalities applied to central serous chorioretinopathy (CSCR). This study aimed to evaluate the efficacy and durability of PDT in CSCR cases unresponsive to at least two SML treatments.MethodsThe study included 26 consecutive eyes of 24 patients (21 males and three females) with chronic CSCR. In all cases

a lack of reduction in subretinal fluid (SRF) levels was noted after at least two consecutive SML sessions. The parameters of best corrected visual acuity (BCVA) and spectral domain optical coherence tomography (SD-OCT) were evaluated at baseline and 1

3 and 12 months post-PDT.ResultsThe mean duration of symptoms in the group was 53.81 ± 39.48 months

the mean age of the patients was 49.26 ± 12.91 years

and the mean subfoveal choroidal thickness (SFCT) was 572.11 ± 116.21 mm. Complete resorption of SRF was observed in 21 out of 26 eyes (80.77%) at 1 month and sustained in 18 cases (69.23%) at 12 months. At 12 months

in the sustained group

BCVA improved significantly from 0.39 ± 0.18 to 0.19 ± 0.2 logMAR (

= 0.01)

central subfoveal thickness (CST) reduced from 316.44 ± 75.83 mm to 197.67 ± 22.99 mm (

0.0001)

and SFCT reduced from 579.28 mm to 446.78 mm (

0.0001).ConclusionsPDT provides the opportunity for the successful treatment of CSCR unresponsive to SML treatment. Improvements are possible even in cases with a long duration of symptoms and significant alterations in retinal morphology. Thus

PDT should be considered for patients with prominently increased choroidal thickness.

关键词

Keywords

Photodynamic therapySubthreshold micropulse laserCentral serous chorioretinopathySybretinal fluid

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