Potential underlying genetic associations between keratoconus and diabetes mellitus

Kristin M. Ates; Amy J. Estes; Yutao Liu

doi:10.1016/j.aopr.2021.100005

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Potential underlying genetic associations between keratoconus and diabetes mellitus

更新时间：2023-11-15

- Potential underlying genetic associations between keratoconus and diabetes mellitus
- AOPR Vol. 1, Issue 1, Pages: 100005(2021)
- 作者机构：
  
  1. Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University,GA,Augusta,USA
  2. Department of Ophthalmology, Medical College of Georgia, Augusta University,GA,Augusta,USA
  3. James and Jean Culver Vision Discovery Institute, Medical College of Georgia, Augusta University,GA,Augusta,USA
  4. Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta University,GA,Augusta,USA
- 作者简介：
- 基金信息：
- DOI：10.1016/j.aopr.2021.100005
  CLC：
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Kristin M. Ates, Amy J. Estes, Yutao Liu. Potential underlying genetic associations between keratoconus and diabetes mellitus. [J]. AOPR 1(1):100005(2021)
DOI：

Kristin M. Ates, Amy J. Estes, Yutao Liu. Potential underlying genetic associations between keratoconus and diabetes mellitus. [J]. AOPR 1(1):100005(2021) DOI： 10.1016/j.aopr.2021.100005.

摘要

Abstract

BackgroundKeratoconus (KC) is the most common ectatic corneal disease, characterized by significantly localized thinning of the corneal stroma. Genetic, environmental, hormonal, and metabolic factors contribute to the pathogenesis of KC. Additionally, multiple comorbidities, such as diabetes mellitus, may affect the risk of KC.

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Keywords

KeratoconusGeneticsDiabetesCollagen crosslinkingOxidative stress

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