Latest Issue
      2023 Year 03 Issue

        Review

      • Hongyan Liu,Jun Cheng,Xiaoyun Zhuang,Benxiang Qi,Fenfen Li,Bining Zhang
        2023, 3(03): 103-111. DOI: 10.1016/j.aopr.2023.03.002
        Abstract：BackgroundGenetic information is stored in the bases of double-stranded DNA. However, the integrity of DNA molecules is constantly threatened by various mutagenic agents, including pollutants, ultraviolet light (UV), and medications. To counteract these environmental damages, cells have established multiple mechanisms, such as producing molecules to identify and eliminate damaged DNA, as well as reconstruct the original DNA structures. Failure or insufficiency of these mechanisms can cause genetic instability. However, the role of genome stability in eye diseases is still under-researched, despite extensive study in cancer biology.  
        Keywords：Genomic instability; Ocular diseases; Retinoblastoma; Cornea; Pterygium   
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      • Xueqi Xiao,Zhiyong Liao,Jian Zou
        2023, 3(03): 126-133. DOI: 10.1016/j.aopr.2023.05.004
        Abstract：BackgroundRetinal diseases characterized with irreversible loss of retinal nerve cells, such as optic atrophy and retinal degeneration, are the main causes of blindness. Current treatments for these diseases are very limited. An emerging treatment strategy is to induce the reprogramming of Müller glial cells to generate new retinal nerve cells, which could potentially restore vision.  
        Keywords：Müller glial cell reprogramming; Genetic regulation; Epigenetic modification; retinal neuron regeneration   
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        Full Length Article

      • Jinglan Li,Siwenyue Zhang,Baoke Hou
        2023, 3(03): 112-118. DOI: 10.1016/j.aopr.2023.05.001
        Abstract：PurposeTo establish a comprehensive treatment strategy and evaluate the efficacy of combination of anti-vascular endothelial growth factor (VEGF) injection, pars plana vitrectomy (PPV), endoscopic pan-retinal photocoagulation (PRP), and endoscopic cyclophotocoagulation (ECP) surgery for neovascular glaucoma (NVG) patients.  
        Keywords：Neovascular glaucoma; Endoscopic cyclophotocoagulation; Pars plana vitrectomy; Pan-retinal photocoagulation; Anti-VEGF   
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        Published：2023-10-19
      • Praneeth Kalva,Rubeel Akram,Priya Mekala,Monica Patel,Sruthi Suresh,Karanjit S. Kooner
        2023, 3(03): 119-125. DOI: 10.1016/j.aopr.2023.05.002
        Abstract：PurposeTo quantitatively measure and compare the vascular morphology in healthy eyes and eyes with primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCTA) scans.  
        Keywords：Optical coherence tomography angiography; Glaucoma; Vessel density   
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      • Jin Xie,Xinyi Zang,Shilan Mao,Jie Sun,Ting Liu,Yunhai Dai
        2023, 3(03): 134-140. DOI: 10.1016/j.aopr.2023.06.001
        Abstract：BackgroundTo report the clinical consequences and laboratory characteristics of late postoperative opacification of a hydrophilic acrylic intraocular lens (US-860UV IOL) as well as the prognosis of IOL replacement.  
        Keywords：Hydrophilic IOL; Opacification; Calcium; IOL replacement   
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        Published：2023-10-19
      • Yongping Wang,Junxia Fu,Huanfen Zhou,Hongen Li,Quangang Xu,Shihui Wei
        2023, 3(03): 141-146. DOI: 10.1016/j.aopr.2023.05.003
        Abstract：PurposeTo observe the clinical and imaging characteristics of radiation-induced optic neuropathy (RION).  
        Keywords：Radiation-induced optic neuropathy (RION); Magnetic resonance imaging (MRI); Optical coherence tomography (OCT); Hyperbaric oxygen therapy (HBOT); High-dose intravenous methyl prednisolone (IVMP)   
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      • Wei Fan,Guangbin Zhang
        2023, 3(03): 147-152. DOI: 10.1016/j.aopr.2023.07.001
        Abstract：PurposeTo evaluate near, intermediate, distance visual acuity and stereopsis after bilateral implantation of Toric intraocular lenses (IOLs) in high myopic patients with astigmatism.  
        Keywords：Toric IOL; Stereopsis; High myopia; Cataract; Near visual acuity   
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