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1. Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne,Cologne,Germany
2. Center for Integrated Oncology (CIO), Aachen-Bonn-Cologne-Duesseldorf,Cologne,Germany
3. Eye Center, Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,China
Published:2024,
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XINCEN HOU, ALEXANDER C. ROKOHL, XUETING LI, et al. Global incidence and prevalence in uveal melanoma. [J]. Aopr, 2024, 4(4): 226-232.
XINCEN HOU, ALEXANDER C. ROKOHL, XUETING LI, et al. Global incidence and prevalence in uveal melanoma. [J]. Aopr, 2024, 4(4): 226-232. DOI: 10.1016/j.aopr.2024.10.001.
PurposeThe most common intraocular cancer in adults is uveal melanoma (UM). This study aimed to investigate and report the incidence and prognosis of UM in different regions of the world.MethodsWe retrieved relevant data on UM from the PubMed database and analyzed its global incidence and prognosis. All data was obtained from a national population-based registry
with publication dates ranging from 2013 to 2023.ResultsThe incidence rates of UM vary across different regions: in the United States
rates were 5.1 per million (1993–2008) and 5.2 per million (1973–2013); in Canada
rates ranged from 3.34 per million (1992–2010) to 5.09 per million (2011–2017); in Republic of Korea
the rate was 0.42 per million (1999–2011); in New Zealand
it was 5.56 per million (2000–2020); in Australia
it was 7.6 per million (1982–2014); and in Europe
rates ranged from 3.1 to 5.8 per million (1995–2002). Among European countries
Sweden (5.6 per million (1960–2009))
Germany (6.41 per million (2009–2015))
Poland (6.67 per million (2010–2017))
and the United Kingdom (10 per million (1999–2010)).ConclusionsThe most common site of occurrence for UM is in the choroid. Limited data suggest a stable trend in UM incidence rates across the included countries
but significant differences in incidence rates exist among different countries and regions
with notably lower rates in Asian countries compared to Europe
North America
and Oceania. In general
the incidence rate in males is slightly higher compared to that in females.
Uveal melanomaIncidenceEpidemiology
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