Global incidence and prevalence of malignant orbital tumors

Weina Zhang; Alexander C. Rokohl; Yongwei Guo; Ke Yao; Wanlin Fan; Ludwig M. Heindl

doi:10.1016/j.aopr.2024.04.002

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Global incidence and prevalence of malignant orbital tumors

Full Length Article | 更新时间：2024-12-14

- Global incidence and prevalence of malignant orbital tumors
- AOPR Vol. 4, Issue 3, Pages: 128-133(2024)
- 作者机构：
  
  1. Department of Ophthalmology, University of Cologne, Faculty of Medicine and University Hospital Cologne,Cologne,Germany
  2. Center for Integrated Oncology (CIO), Aachen-Bonn-Cologne-Duesseldorf,Cologne,Germany
  3. Eye Center, The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,China
- 作者简介：
- 基金信息：
- DOI：10.1016/j.aopr.2024.04.002
  CLC：
- Published：2024，
- 稿件说明：
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WEINA ZHANG, ALEXANDER C. ROKOHL, YONGWEI GUO, et al. Global incidence and prevalence of malignant orbital tumors. [J]. Aopr, 2024, 4(3): 128-133.
DOI：

WEINA ZHANG, ALEXANDER C. ROKOHL, YONGWEI GUO, et al. Global incidence and prevalence of malignant orbital tumors. [J]. Aopr, 2024, 4(3): 128-133. DOI： 10.1016/j.aopr.2024.04.002.

摘要

Abstract

PurposeAims to provide an overview of the contemporary epidemiology of malignant orbital tumors by analyzing population-based incidence patterns across various regions worldwide.MethodsIn this article

we retrieved orbital malignancy data from the MEDLINE database and analyzed the incidence and prevalence of orbital malignancies worldwide. We performed the literature search by searching on the Mesh terms for malignant orbital tumors ("orbital"

"tumor"

"lymphoma"

"malignant"

"cancer"

"incidence"

and "epidemiology"). All included studies were published between 1993 and 2023 and were written in English.ResultsOcular or ophthalmic lymphoma most frequently occurred in the orbit

with a prevalence ranging from 47% to 54%. The incidence of malignant orbital tumors was increasing in the USA (2.0 per million (1981–1993)

Netherlands (0.86 (1981–1985) to 2.49 (2001–2005) per million) and South Korea (0.3–0.8 per million (1999–2016))

respectively. Ophthalmic lymphoma which includes orbit lymphoma was increasing in Canada (0.17–1.47 per million (1992–2010))

Denmark (0.86 per million (1981–1985) to 2.49 per million (2001–2005))

respectively.ConclusionsThe predominant primary malignant orbital tumor in adults was lymphoma. Ocular or ophthalmic lymphoma most frequently occured in the orbit. The limited data available suggested an increasing trend in the incidence of malignant orbital tumors in each country included

which were mainly attributed to the increase in lymphoma. Generally

incidence rates were found to increase with advancing age

with no difference between males and females.

关键词

Keywords

Orbital tumorLymphomaMalignantIncidenceEpidemiology

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