The necessity of pretreatment with 0.1% pranoprofen for femtosecond-assisted cataract surgery: A single-center, randomized controlled trial
- AOPR Vol. 3, Issue 4, Pages: 153-158(2023)
- 作者机构：
1. Department of Ophthalmology, Daping Hospital, Army Medical University,Chongqing,China
2. Cancer Center, Daping Hospital, Army Medical University,Chongqing,China
3. Department of Ophthalmology, Xinqiao Hospital, Army Medical University,Chongqing,China
- 作者简介：
- 基金信息：
DOI：10.1016/j.aopr.2023.07.002
CLC：
扫 描 看 全 文
The necessity of pretreatment with 0.1% pranoprofen for femtosecond-assisted cataract surgery: A single-center, randomized controlled trial. [J]. AOPR 3(4):153-158(2023)
The necessity of pretreatment with 0.1% pranoprofen for femtosecond-assisted cataract surgery: A single-center, randomized controlled trial. [J]. AOPR 3(4):153-158(2023) DOI： 10.1016/j.aopr.2023.07.002.
摘要
Purpose,To explore the effect of the variation of pupil diameter (PD) and intraocular pressure (IOP) induced by femtosecond laser treatment on the subsequent phacoemulsfication and intraocular lens implantation. And whether the application of 0.1% pranoprofen could significantly reduce the miosis and increased IOP caused by femtosecond laser treatment in femtosecond laser-assisted cataract surgery (FLACS).,Methods,In this study, patients were pretreated with (trial group) or without (control group) topical 0.1% pranoprofen. The PD and IOP were measured at different time points within 30 min after the completion of the femtosecond laser treatment.,Results,The comparisons of the two groups showed the PD of patients pretreated with 0.1% pranoprofen was significantly larger than that of the control only at 15 min after FLACS (,P, = 0.046), and there was no significant difference in IOP at any time point (,P, ,>, 0.05). Neither the ratio of significant miosis (PD ≤ 5 mm) nor intraocular hypertension (IOP ≥30 mmHg) was significantly different between the control group (1.72%, 6.67%) and the trial group (1%, 4.17%) (,P, ,>, 0.05).,Conclusions,The PD and IOP of patients undergoing FLACS showed fluctuations within a small range. The rates of significant miosis and intraocular hypertension are very low, it is safe for surgeons to complete the follow-up procedures within 30 min after femtosecond laser treatment. Pretreatment with 0.1% pranoprofen exerted a slight, albeit significant prophylactic effect preventing pupil miosis. However, it provided only a limited benefit in patients undergoing FLACS without other complications.
Abstract
Purpose,To explore the effect of the variation of pupil diameter (PD) and intraocular pressure (IOP) induced by femtosecond laser treatment on the subsequent phacoemulsfication and intraocular lens implantation. And whether the application of 0.1% pranoprofen could significantly reduce the miosis and increased IOP caused by femtosecond laser treatment in femtosecond laser-assisted cataract surgery (FLACS).,Methods,In this study, patients were pretreated with (trial group) or without (control group) topical 0.1% pranoprofen. The PD and IOP were measured at different time points within 30 min after the completion of the femtosecond laser treatment.,Results,The comparisons of the two groups showed the PD of patients pretreated with 0.1% pranoprofen was significantly larger than that of the control only at 15 min after FLACS (,P, = 0.046), and there was no significant difference in IOP at any time point (,P, ,>, 0.05). Neither the ratio of significant miosis (PD ≤ 5 mm) nor intraocular hypertension (IOP ≥30 mmHg) was significantly different between the control group (1.72%, 6.67%) and the trial group (1%, 4.17%) (,P, ,>, 0.05).,Conclusions,The PD and IOP of patients undergoing FLACS showed fluctuations within a small range. The rates of significant miosis and intraocular hypertension are very low, it is safe for surgeons to complete the follow-up procedures within 30 min after femtosecond laser treatment. Pretreatment with 0.1% pranoprofen exerted a slight, albeit significant prophylactic effect preventing pupil miosis. However, it provided only a limited benefit in patients undergoing FLACS without other complications.
关键词
Pupil diameterIntraocular pressureFemtosecondCataract
Keywords
Pupil diameterIntraocular pressureFemtosecondCataract
references
1 Z. Nagy, A. Takacs, T. Filkorn, et al.Initial clinical evaluation of an intraocular femtosecond laser in cataract surgery J Refract Surg, 25 (12) (2009), pp. 1053-1060, 10.3928/1081597x-20091117-04
2 M. Popovic, X. Campos-Moller, M.B. Schlenker, et al.Efficacy and safety of femtosecond laser-assisted cataract surgery compared with manual cataract surgery: a meta-analysis of 14 567 eyes Ophthalmology, 123 (10) (2016), pp. 2113-2126, 10.1016/j.ophtha.2016.07.005
3 T.A. Berk, M.B. Schlenker, X. Campos-Moller, et al.Visual and refractive outcomes in manual versus femtosecond laser-assisted cataract surgery: a single-center retrospective cohort analysis of 1838 Eyes Ophthalmology, 125 (8) (2018), pp. 1172-1180, 10.1016/j.ophtha.2018.01.028
4 H.W. Roberts, V.K. Wagh, D.L. Sullivan, et al.A randomized controlled trial comparing femtosecond laser-assisted cataract surgery versus conventional phacoemulsification surgery J Cataract Refract Surg, 45 (1) (2019), pp. 11-20, 10.1016/j.jcrs.2018.08.033
5 A.Y. Yu, C.X. Lin, Q.M. Wang, et al.Safety of femtosecond laser-assisted cataract surgery: assessment of aqueous humour and lens capsule Acta Ophthalmol, 94 (7) (2016), pp. e534-e540, 10.1111/aos.13022
6 J.H. Jun, Y.S. Yoo, S.A. Lim, et al.Effects of topical ketorolac tromethamine 0.45% on intraoperative miosis and prostaglandin E2 release during femtosecond laser-assisted cataract surgery J Cataract Refract Surg, 43 (4) (2017), pp. 492-497, 10.1016/j.jcrs.2017.01.011
7 N.S. Br J OphthalmolAnisimova, L.B. Arbisser, G. Petrovski, et al.Effect of NSAIDs on pupil diameter and expression of aqueous humor cytokines in FLACS versus conventional phacoemulsification J Refract Surg, 34 (10) (2018), pp. 646-652, 10.3928/1081597x-20180814-02
8 H. Chen, H. Lin, W. Chen, et al.Topical 0.1% bromfenac sodium for intraoperative miosis prevention and prostaglandin E2 inhibition in femtosecond laser-assisted cataract surgery J Ocul Pharmacol Therapeut, 33 (3) (2017), pp. 193-201, 10.1089/jop.2016.0114
9 FJ. ArevaloRetinal complications after laser-assisted in situ keratomileusis (LASIK) Curr Opin Ophthalmol, 15 (3) (2004), pp. 184-191, 10.1097/01.icu.0000120674.27548.9c
10 N.B. Baig, G.P. Cheng, J.K. Lam, et al.Intraocular pressure profiles during femtosecond laser-assisted cataract surgery J Cataract Refract Surg, 40 (11) (2014), pp. 1784-1789, 10.1016/j.jcrs.2014.04.026
11 J.D. Jensen, T. Boulter, N.G. Lambert, et al.Intraocular pressure study using monitored forced-infusion system phacoemulsification technology J Cataract Refract Surg, 42 (5) (2016), pp. 768-771, 10.1016/j.jcrs.2016.01.045
12 J.H. Jun, K.Y. Hwang, S.D. Chang, et al.Pupil-size alterations induced by photodisruption during femtosecond laser-assisted cataract surgery J Cataract Refract Surg, 41 (2) (2015), pp. 278-285, 10.1016/j.jcrs.2014.10.027
13 M.Z. Popiela, T. Young-Zvandasara, P. Nidamanuri, et al.Factors influencing pupil behaviour during femtosecond laser assisted cataract surgery Contact Lens Anterior Eye, 42 (3) (2019), pp. 295-298, 10.1016/j.clae.2018.10.010
14 M. Ibarz, J.L. Hernandez-Verdejo, G. Bolivar, et al.Porcine model to evaluate real-time intraocular pressure during femtosecond laser cataract surgery Curr Eye Res, 41 (4) (2016), pp. 507-512, 10.3109/02713683.2015.1023459
15 G.P. Williams, H.P. Ang, B.L. George, et al.Comparison of intra-ocular pressure changes with liquid or flat applanation interfaces in a femtosecond laser platform Sci Rep, 5 (2015), Article 14742, 10.1038/srep14742
16 A. Mirshahi, A. Schneider, C. Latz, et al.Perioperative pupil size in low-energy femtosecond laser-assisted cataract surgery PLoS One, 16 (5) (2021), Article e0251549, 10.1371/journal.pone.0251549
17 S.J. Bali, C. Hodge, M. Lawless, et al. Early experience with the femtosecond laser for cataract surgery Ophthalmology, 119 (5) (2012), pp. 891-899, 10.1016/j.ophtha.2011.12.025
18 E. Darian-Smith, A.R. Howie, R.G. Abell, et al.Intraocular pressure during femtosecond laser pretreatment: comparison of glaucomatous eyes and nonglaucomatous eyes J Cataract Refract Surg, 41 (2) (2015), pp. 272-277, 10.1016/j.jcrs.2014.10.026
19 T. Schultz, I. Conrad-Hengerer, F.H. Hengerer, et al.Intraocular pressure variation during femtosecond laser-assisted cataract surgery using a fluid-filled interface J Cataract Refract Surg, 39 (1) (2013), pp. 22-27, 10.1016/j.jcrs.2012.10.038
20 P. Sperl, C. Strohmaier, H. Kraker, et al.Intraocular pressure course during the femtosecond laser-assisted cataract surgery in porcine cadaver eyes Invest Ophthalmol Vis Sci, 58 (14) (2017), pp. 6457-6461, 10.1167/iovs.17-21948
21 T. Schultz, S.C. Joachim, M. Szuler, et al.NSAID pretreatment inhibits prostaglandin release in femtosecond laser-assisted cataract surgery J Refract Surg, 31 (12) (2015), pp. 791-794, 10.3928/1081597X-20151111-01
0
Views
0
下载量
0
CSCD
- Meta-XMLDownload
- BibTeXDownload
- EndnoteDownload
- RefMan Download
- NoteExpressDownload
- NoteFirstDownload
Publicity Resources
Related Articles
Related Author
Related Institution
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19
京公网安备11010802024621 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.